概 述
|
Full name: |
poly (ADP-ribose) polymerase family, member 3 |
|
Synonyms: |
IRT1; ARTD3; ADPRT3; ADPRTL2; ADPRTL3; PADPRT-3 |
|
Swissprot: |
Q9Y6F1 |
|
Gene Accession: |
BC014260 |
|
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
|
Expression system: |
Escherichia coli |
|
Tags: |
His tag C-Terminus, GST tag N-Terminus |
|
Background: |
The protein encoded by this gene belongs to the PARP family. These enzymes modify nuclear proteins by poly-ADP-ribosylation, which is required for DNA repair, regulation of apoptosis, and maintenance of genomic stability. This gene encodes the poly(ADP-ribosyl)transferase 3, which is preferentially localized to the daughter centriole throughout the cell cycle. Alternatively spliced transcript variants encoding different isoforms have been identified. |
