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Full name: |
nuclear receptor subfamily 4, group A, member 1 |
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Synonyms: |
HMR; N10; TR3; NP10; GFRP1; NAK-1; NGFIB; NUR77 |
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Swissprot: |
P22736 |
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Gene Accession: |
BC016147 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
This gene encodes a member of the steroid-thyroid hormone-retinoid receptor superfamily. Expression is induced by phytohemagglutinin in human lymphocytes and by serum stimulation of arrested fibroblasts. The encoded protein acts as a nuclear transcription factor. Translocation of the protein from the nucleus to mitochondria induces apoptosis. Multiple transcript variants encoding different isoforms have been found for this gene. |
