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  • 产品名称：MASP1 抗原（重组蛋白）

  • 产品型号：1mg
  • 产品厂商：通蔚生物
  • 产品价格：3580
  • 产品库存：35
  • 产品文档：
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简单介绍：
MASP1 抗原（重组蛋白）始终以服务国内先进的研究机构和国内高校为己任，在不懈的探索和实践中，长期以来一直注重品牌建设，始终把抓产品质量作为所有工作的重中之重，所生产销售的各类试剂受到广大用户的广泛认可和信赖。有关的一切操作和事项，都严格依照步骤依据，为了保护结果真实有效，应该以英文版说明书为准。
详情介绍：



中文名称： MASP1 抗原（重组蛋白）

英文名称： MASP1 Antigen (Recombinant Protein)

别     名：  3MC1; MAP1; MASP; RaRF; CRARF; MASP3; MAp44; PRSS5; CRARF1

相关类别： 抗原

储     存：  冷冻（-20℃）  

概     述

Fusion protein corresponding to a region derived from 449-699 amino acids of humanMASP1


技术规格

Full name:

mannan binding lectin serine peptidase 1

Synonyms:

3MC1; MAP1; MASP; RaRF; CRARF; MASP3; MAp44; PRSS5; CRARF1

Swissprot:

P48740

Gene Accession:

BC106945

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This gene encodes a serine protease that functions as a component of the lectin pathway of complement activation. The complement pathway plays an essential role in the innate and adaptive immune response. The encoded protein is synthesized as a zymogen and is activated when it complexes with the pathogen recognition molecules of lectin pathway, the mannose-binding lectin and the ficolins. This protein is not directly involved in complement activation but may play a role as an amplifier of complement activation by cleaving complement C2 or by activating another complement serine protease, MASP-2. The encoded protein is also able to cleave fibrinogen and factor XIII and may may be involved in coagulation. A splice variant of this gene which lacks the serine protease domain functions as an inhibitor of the complement pathway. Alternate splicing results in multiple transcript variants.







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