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  • 产品名称：LSM10 抗原（重组蛋白）

  • 产品型号：100ug
  • 产品厂商：通蔚生物
  • 产品价格：800
  • 产品库存：35
  • 产品文档：
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简单介绍：
LSM10 抗原（重组蛋白）始终以服务国内先进的研究机构和国内高校为己任，在不懈的探索和实践中，长期以来一直注重品牌建设，始终把抓产品质量作为所有工作的重中之重，所生产销售的各类试剂受到广大用户的广泛认可和信赖。有关的一切操作和事项，都严格依照步骤依据，为了保护结果真实有效，应该以英文版说明书为准。
详情介绍：


中文名称： LSM10 抗原（重组蛋白）

英文名称： LSM10 Antigen (Recombinant Protein)

别     名：  LSM10, U7 small nuclear RNA associated; MST074; MSTP074

储     存：  冷冻（-20℃）

相关类别： 抗原

概     述

Fusion protein corresponding to a region derived from 1-123 amino acids of human LSM10

技术规格

Full name:

LSM10, U7 small nuclear RNA associated

Synonyms:

MST074; MSTP074

Swissprot:

Q969L4

Gene Accession:

BC007623

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

LSm10 (U7 snRNA-associated Sm-like protein LSm10) is a nuclear protein that belongs to the snRNP (small nuclear ribonucleoproteins) Sm protein family. The survival of motor neurons (SMN) complex mediates the assembly of snRNPs involved in splicing and histone RNA processing. A crucial step in this process is the binding of Sm proteins onto the SMN protein. LSm10 and LSm11, mammalian homologs of the yeast Sm proteins D1 and D2, are important for U7 snRNP function and subcellular localization. U7 snRNP is an RNA molecule involved in the splicing of animal histone pre-mRNAs. Lsm10 and Lsm11 also associate with pICln (Chloride ion current inducer protein), which interacts with Sm proteins to inhibit their assembly on U RNA. LSm10 interactions with U7 snRNA and pICln may provide the means for using modified U7 snRNA derivatives to alter specific pre-mRNA splicing events, potentially leading to advances in antisense gene therapy.





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