概 述
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Full name: |
kelch-like family member 9 |
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Swissprot: |
Q9P2J3 |
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Gene Accession: |
NP_061335 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
The BTB (Broad-Complex, Tramtrack and Bric a brac) domain, also known as the POZ (Poxvirus and Zinc finger) domain, is an N-terminal homodimerization domain that contains multiple copies of kelch repeats and/or C2H2-type zinc fingers. Proteins that contain BTB domains are thought to be involved in transcriptional regulation via control of chromatin structure and function. KLHL9 (kelch-like 9) is a 617 amino acid protein containing one BACK (BTB/kelch associated) domain, six kelch repeats and a BTB/POZ domain. KLHL9 is believed to play a role in protein ubiquitination and may function as a substrate-specific adapters of an E3 ubiquitin-protein ligase complex with CUL-3. |
