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  • 产品名称:KEAP1 抗原(重组蛋白)

  • 产品型号:100ug
  • 产品厂商:通蔚生物
  • 产品价格:800
  • 产品库存:35
  • 产品文档:
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中文名称: KEAP1 抗原(重组蛋白)

英文名称: KEAP1 Antigen (Recombinant Protein)

别     名:  kelch-like ECH-associated protein 1; INrf2; KLHL19

储     存:  冷冻(-20℃)

相关类别: 抗原

概     述
 
Fusion protein corresponding to C terminal 300 amino acids of human KEAP1

技术规格

Full name:

kelch-like ECH-associated protein 1

Synonyms:

INrf2; KLHL19

Swissprot:

Q14145

Gene Accession:

BC002417

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This gene encodes a protein containing KELCH-1 like domains, as well as a BTB/POZ domain. Kelch-like ECH-associated protein 1 interacts with NF-E2-related factor 2 in a redox-sensitive manner and the dissociation of the proteins in the cytoplasm is followed by transportation of NF-E2-related factor 2 to the nucleus. This interaction results in the expression of the catalytic subunit of gamma-glutamylcysteine synthetase. Two alternatively spliced transcript variants encoding the same isoform have been found for this gene.





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