中文名称： 兔抗MCAM多克隆抗体
英文名称： Anti-MCAM rabbit polyclonal antibody
别 名： CD146, MUC18
相关类别： 一抗
储 存： 冷冻（-20℃）
宿 主： Rabbit
抗 原： MCAM
反应种属： Human
标 记 物： Unconjugate
克隆类型： rabbit polyclonal
技术规格
|
Background: |
Plays a role in cell adhesion, and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue. Its expression may allow melanoma cells to interact with cellular elements of the vascular system, thereby enhancing hematogeneous tumor spread. Could be an adhesion molecule active in neural crest cells during embryonic development. Acts as surface receptor that triggers tyrosine phosphorylation of FYN and PTK2/FAK1, and a transient increase in the intracellular calcium concentration. |
|
Applications: |
ELISA, WB, IHC |
|
Name of antibody: |
MCAM |
|
Immunogen: |
Synthetic peptide of human MCAM |
|
Full name: |
melanoma cell adhesion molecule |
|
Synonyms: |
CD146; MUC18; HEMCAM; METCAM; MelCAM |
|
SwissProt: |
P43121 |
|
ELISA Recommended dilution: |
5000-10000 |
|
IHC positive control: |
Human thyroid cancer and Human ovarian cancer |
|
IHC Recommend dilution: |
40-200 |
|
WB Predicted band size: |
72 kDa |
|
WB Positive control: |
Human leiomyosarcoma tissue lysate |
|
WB Recommended dilution: |
500-2000 |
