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  • 产品名称：COMT 抗原（重组蛋白）

  • 产品型号：1mg
  • 产品厂商：通蔚生物
  • 产品价格：3580
  • 产品库存：35
  • 产品文档：
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我司 COMT 抗原（重组蛋白）客户提供上等的产品和服务而自豪。我司拥有经验丰富的化学师严格控制化学品的质量，技术服务人员随时可以回答您有关产品的任何问题，向客户提供100%的满意服。客户需提供代测样本，可以长期免费代测服务，全程提供技术支持。
详情介绍：


中文名称： COMT 抗原（重组蛋白）

英文名称： COMT Antigen (Recombinant Protein)

别     名：  catechol-O-methyltransferase; HEL-S-98n

储     存：  冷冻（-20℃）

相关类别： 抗原

概     述

Fusion protein corresponding to a region derived from 27-271 amino acids of human COMT

技术规格

Full name:

catechol-O-methyltransferase

Synonyms:

HEL-S-98n

Swissprot:

P21964

Gene Accession:

BC011935

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

Catechol-O-methyltransferase catalyzes the transfer of a methyl group from S-adenosylmethionine to catecholamines, including the neurotransmitters dopamine, epinephrine, and norepinephrine. This O-methylation results in one of the major degradative pathways of the catecholamine transmitters. In addition to its role in the metabolism of endogenous substances, COMT is important in the metabolism of catechol drugs used in the treatment of hypertension, asthma, and Parkinson disease. COMT is found in two forms in tissues, a soluble form (S-COMT) and a membrane-bound form (MB-COMT). The differences between S-COMT and MB-COMT reside within the N-termini. Several transcript variants are formed through the use of alternative translation initiation sites and promoters.






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