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  • 产品名称:USP2抗原(重组蛋白)

  • 产品型号:1mg
  • 产品厂商:通蔚生物
  • 产品价格:3580
  • 产品库存:35
  • 产品文档:
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详情介绍:


中文名称: USP2抗原(重组蛋白)

英文名称: USP2 Antigen (Recombinant Protein)

别     名:  USP9; UBP41

储     存:  冷冻(-20℃)

相关类别: 抗原

概     述:

Fusion protein corresponding to a region derived from C terminal 250 amino acids of human USP2

技术规格

Full name:

ubiquitin specific peptidase 2

Synonyms:

USP9; UBP41

Swissprot:

O75604

Gene Accession:

BC002854

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This gene encodes a member of the family of de-ubiquitinating enzymes, which belongs to the peptidase C19 superfamily. The encoded protein is a ubiquitin-specific protease which is required for TNF-alpha (tumor necrosis factor alpha) -induced NF-kB (nuclear factor kB) signaling. This protein deubiquitinates polyubiquitinated target proteins such as fatty acid synthase, murine double minute 2 (MDM2), MDM4/MDMX and cyclin D1. MDM2 and MDM4 are negative regulators of the p53 tumor suppressor and cyclin D1 is required for cell cycle G1/S transition. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.





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