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  • 产品名称:TSLP 抗原(重组蛋白)

  • 产品型号:100ug
  • 产品厂商:通蔚生物
  • 产品价格:800
  • 产品库存:35
  • 产品文档:
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详情介绍:

中文名称: TSLP 抗原(重组蛋白)

英文名称: TSLP Antigen (Recombinant Protein)

别     名:  Thymic stromal lymphopoietin

储     存:  冷冻(-20℃)

相关类别: 抗原

概    述:

Fusion protein corresponding to a region derived from 100-159 amino acids of human TSLP
    
技术规格

Full name:

Thymic stromal lymphopoietin

Swissprot:

Q969D9

Gene Accession:

BC016720

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This gene encodes a hemopoietic cytokine proposed to signal through a heterodimeric receptor complex composed of the thymic stromal lymphopoietin receptor and the IL-7R alpha chain. It mainly impacts myeloid cells and induces the release of T cell-attracting chemokines from monocytes and enhances the maturation of CD11c(+) dendritic cells. The protein promotes T helper type 2 (TH2) cell responses that are associated with immunity in various inflammatory diseases, including asthma, allergic inflammation and chronic obstructive pulmonary disease. The protein is therefore considered a potential therapeutic target for the treatment of such diseases. Alternative splicing of this gene results in multiple transcript variants.





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