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  • 产品名称:TRIP4抗原(重组蛋白)

  • 产品型号:100ug
  • 产品厂商:通蔚生物
  • 产品价格:800
  • 产品库存:35
  • 产品文档:
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详情介绍:

中文名称: TRIP4抗原(重组蛋白)

英文名称: TRIP4 Antigen (Recombinant Protein)

别     名:  ASC1; ASC-1; HsT17391

储     存:  冷冻(-20℃)

相关类别: 抗原

概     述:

Fusion protein corresponding to C terminal 250 amino acids of human TRIP4

技术规格

Full name:

thyroid hormone receptor interactor 4

Synonyms:

ASC1; ASC-1; HsT17391

Swissprot:

Q15650

Gene Accession:

BC012448

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

Activating signal co-integrator-1 (ASC-1), originally identified as TRIP4, is a transcriptional co-activator of nuclear receptors that associates with specific components of the RNA polymerase II complex and binds the basal transcription factors TBP and TFIIA. ASC-1 functions with the transcription integrators SRC-1 and CBP/p300 through its zinc finger motif and is dependent on their ligand-dependent transactivation domain, AF2. Endogenous ASC-1 in HeLa cells is predominantly a nuclear protein. Under conditions of serum starvation, ASC-1 localizes to the cytoplasm.





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