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  • 产品名称：TNK2 抗原（重组蛋白）

  • 产品型号：100ug
  • 产品厂商：通蔚生物
  • 产品价格：800
  • 产品库存：35
  • 产品文档：
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详情介绍：

中文名称： TNK2 抗原（重组蛋白）

英文名称： TNK2 Antigen (Recombinant Protein)

别     名：  tyrosine kinase, non-receptor, 2; ACK; ACK1; ACK-1; p21cdc42Hs

储     存：  冷冻（-20℃）

相关类别： 抗原

概     述：

Fusion protein corresponding to C terminal 250 amino acids of human TNK2
    
技术规格

Full name:

tyrosine kinase, non-receptor, 2

Synonyms:

ACK; ACK1; ACK-1; p21cdc42Hs

Swissprot:

Q07912

Gene Accession:

BC028164

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This gene encodes a tyrosine kinase that binds Cdc42Hs in its GTP-bound form and inhibits both the intrinsic and GTPase-activating protein (GAP)-stimulated GTPase activity of Cdc42Hs. This binding is mediated by a unique sequence of 47 amino acids C-terminal to an SH3 domain. The protein may be involved in a regulatory mechanism that sustains the GTP-bound active form of Cdc42Hs and which is directly linked to a tyrosine phosphorylation signal transduction pathway. Several alternatively spliced transcript variants have been identified from this gene, but the full-length nature of only two transcript variants has been determined.





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