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  • 产品名称:TIMP2 抗原(重组蛋白)

  • 产品型号:100ug
  • 产品厂商:通蔚生物
  • 产品价格:800
  • 产品库存:35
  • 产品文档:
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详情介绍:

中文名称: TIMP2 抗原(重组蛋白)

英文名称: TIMP2 Antigen (Recombinant Protein)

别     名:  TIMP metallopeptidase inhibitor 2; CSC-21K

储     存:  冷冻(-20℃)

相关类别: 抗原

概     述:
  
Fusion protein corresponding to a region derived from 30-220 amino acids of human TIMP2
  
技术规格

Full name:

TIMP metallopeptidase inhibitor 2

Synonyms:

CSC-21K

Swissprot:

P16035

Gene Accession:

BC052605

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This gene is a member of the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix. In addition to an inhibitory role against metalloproteinases, the encoded protein has a unique role among TIMP family members in its ability to directly suppress the proliferation of endothelial cells. As a result, the encoded protein may be critical to the maintenance of tissue homeostasis by suppressing the proliferation of quiescent tissues in response to angiogenic factors, and by inhibiting protease activity in tissues undergoing remodelling of the extracellular matrix.





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