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  • 产品名称:MCM3AP抗原(重组蛋白)

  • 产品型号:1mg
  • 产品厂商:通蔚生物
  • 产品价格:3580
  • 产品库存:35
  • 产品文档:
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简单介绍:
MCM3AP抗原(重组蛋白)大部分抗体的运输条件是一般的运输过程需要1-2周的时间,所以是在4℃的条件下来完成的,4℃运输*主要的目的是为了避免反复冻融对抗体活性的损害(如果使用干冰运输,那么收到时抗体是冻起来的,为了分装就需要解冻,这就多了一次冻融的过程),所以运输过程中优良避免干冰运输!
详情介绍:
中文名称: MCM3AP抗原(重组蛋白)

英文名称: MCM3AP Antigen (Recombinant Protein)

别     名:  GANP; SAC3; MAP80

储     存:  冷冻(-20℃)

相关类别: 抗原

概     述:

Fusion protein corresponding to N terminal 150 amino acids of human MCM3AP

技术规格

Full name:

minichromosome maintenance complex component 3 associated protein

Synonyms:

GANP; SAC3; MAP80

Swissprot:

O60318

Gene Accession:

BC104958

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

The minichromosome maintenance protein 3 (MCM3) is one of the MCM proteins essential for the initiation of DNA replication. The protein encoded by this gene is a MCM3 binding protein. It was reported to have phosphorylation-dependent DNA-primase activity, which was up-regulated in antigen immunization induced germinal center. This protein was demonstrated to be an acetyltransferase that acetylates MCM3 and plays a role in DNA replication. The mutagenesis of a nuclear localization signal of MCM3 affects the binding of this protein with MCM3, suggesting that this protein may also facilitate MCM3 nuclear localization. This gene is expressed in the brain or in neuronal tissue. An allelic variant encoding amino acid Lys at 915, instead of conserved Glu, has been identified in patients with mild intellectual disability.





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