别 名： ZNF393; Zfp393; RP4-675G8.1
储 存： 冷冻（-20℃）
概 述：
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Full name: |
Kruppel-like factor 17 |
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Synonyms: |
ZNF393; Zfp393; RP4-675G8.1 |
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Swissprot: |
Q5JT82 |
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Gene Accession: |
BC049844 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
Krueppel-like factor 17 is a protein that in humans is encoded by the KLF17 gene. Transcription repressor that binds to the promoter of target genes and prevents their expression. Acts as a negative regulator of epithelial-mesenchymal transition and metastasis in breast cancer. Specifically binds the 5'-CACCC-3' sequence in the promoter of ID1, a key metastasis regulator in breast cancer, and repress its expression. May be a germ cell-specific transcription factor that plays important roles in spermatid differentiation and oocyte development. |
