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  • 产品名称：GP1BA抗原（重组蛋白）

  • 产品型号：1mg
  • 产品厂商：通蔚生物
  • 产品价格：3580
  • 产品库存：35
  • 产品文档：
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简单介绍：
我司 GP1BA抗原（重组蛋白）免费为您提供产品*新报价、用途、规格、说明书、使用操作等相关方面的咨询。我司自有工厂自主研发，高效省时，我司有大量现货库存，到货及时。欢迎您来电或联系在线客服咨询该产品的详细信息，真诚希望广大客户对我们的工作和服务提出宝贵的意见和建议，以便更好的适应新的变化，提供更贴心的服务。
详情介绍：
中文名称： GP1BA抗原（重组蛋白）

英文名称： GP1BA Antigen (Recombinant Protein)

别     名：  BSS; GP1B; VWDP; CD42B; GPIbA; BDPLT1; BDPLT3; DBPLT3; CD42b-alpha

储     存：  冷冻（-20℃）

相关类别： 抗原

概     述：

Fusion protein corresponding to a region derived from 17-300 amino acids of human GP1BA

技术规格

Full name:

glycoprotein Ib (platelet), alpha polypeptide

Synonyms:

BSS; GP1B; VWDP; CD42B; GPIbA; BDPLT1; BDPLT3; DBPLT3; CD42b-alpha

Swissprot:

P07359

Gene Accession:

BC027955

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

Glycoprotein Ib (GP Ib) is a platelet surface membrane glycoprotein composed of a heterodimer, an alpha chain and a beta chain, that is linked by disulfide bonds. The Gp Ib functions as a receptor for von Willebrand factor (VWF). The complete receptor complex includes noncovalent association of the alpha and beta subunits with platelet glycoprotein IX and platelet glycoprotein V. The binding of the GP Ib-IX-V complex to VWF facilitates initial platelet adhesion to vascular subendothelium after vascular injury, and also initiates signaling events within the platelet that lead to enhanced platelet activation, thrombosis, and hemostasis. This gene encodes the alpha subunit. Mutations in this gene result in Bernard-Soulier syndromes and platelet-type von Willebrand disease. The coding region of this gene is known to contain a polymophic variable number tandem repeat (VNTR) domain that is associated with susceptibility to nonarteritic anterior ischemic optic neuropathy.





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