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  • 产品名称:GADD45A抗原(重组蛋白)

  • 产品型号:1mg
  • 产品厂商:通蔚生物
  • 产品价格:3580
  • 产品库存:35
  • 产品文档:
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详情介绍:
中文名称: GADD45A抗原(重组蛋白)

英文名称: GADD45A Antigen (Recombinant Protein)

别     名:  DDIT1; GADD45

储     存:  冷冻(-20℃)

相关类别: 抗原

概     述:
   
Fusion protein corresponding to a region derived from 5-165 amino acids of human GADD45A

技术规格

Full name:

growth arrest and DNA-damage-inducible, alpha

Synonyms:

DDIT1; GADD45

Swissprot:

P24522

Gene Accession:

BC011757

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The protein encoded by this gene responds to environmental stresses by mediating activation of the p38/JNK pathway via MTK1/MEKK4 kinase. The DNA damage-induced transcription of this gene is mediated by both p53-dependent and -independent mechanisms. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.





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