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  • 产品名称:GAB2抗原(重组蛋白)

  • 产品型号:1mg
  • 产品厂商:通蔚生物
  • 产品价格:3580
  • 产品库存:35
  • 产品文档:
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详情介绍:
中文名称: GAB2抗原(重组蛋白)

英文名称: GAB2 Antigen (Recombinant Protein)

储     存:  冷冻(-20℃)

相关类别: 抗原

概     述:

Fusion protein corresponding to C terminal 250 amino acids of human GAB2

技术规格

Full name:

GRB2-associated binding protein 2

Swissprot:

Q9UQC2

Gene Accession:

BC131711

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This gene is a member of the GRB2-associated binding protein (GAB) gene family. These proteins contain pleckstrin homology (PH) domain, and bind SHP2 tyrosine phosphatase and GRB2 adapter protein. They act as adapters for transmitting various signals in response to stimuli through cytokine and growth factor receptors, and T- and B-cell antigen receptors. The protein encoded by this gene is the principal activator of phosphatidylinositol-3 kinase in response to activation of the high affinity IgE receptor. Two alternatively spliced transcripts encoding different isoforms have been described for this gene.





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