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  • 产品名称：ELOB抗原（重组蛋白）

  • 产品型号：1mg
  • 产品厂商：通蔚生物
  • 产品价格：3580
  • 产品库存：35
  • 产品文档：
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简单介绍：
ELOB抗原（重组蛋白）公司秉承“专注品质、信守承诺、积极沟通、chuang新服务”的企业文化积极参与生物领域的技术chuang新和技术服务，力求为我国科研事业添砖加瓦，严格的质控体系，建立和完善企业制度，创造性发展，客户的满意就是我们的宗旨。
详情介绍：
中文名称： ELOB抗原（重组蛋白）

英文名称： ELOB Antigen (Recombinant Protein)

别     名：  SIII; TCEB2

储     存：  冷冻（-20℃）

相关类别： 抗原

概     述：

Fusion protein corresponding to a region derived from 1-118 amino acids of human ELOB

技术规格

Full name:

elongin B

Synonyms:

SIII; TCEB2

Swissprot:

Q15370

Gene Accession:

BC013306

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This gene encodes the protein elongin B, which is a subunit of the transcription factor B (SIII) complex. The SIII complex is composed of elongins A/A2, B and C. It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. Elongin A functions as the transcriptionally active component of the SIII complex, whereas elongins B and C are regulatory subunits. Elongin A2 is specifically expressed in the testis, and capable of forming a stable complex with elongins B and C. The von Hippel-Lindau tumor suppressor protein binds to elongins B and C, and thereby inhibits transcription elongation. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene. Pseudogenes have been identified on chromosomes 11 and 13. [provided by RefSeq, Aug 2008]





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