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  • 产品名称：EID1抗原（重组蛋白）

  • 产品型号：1mg
  • 产品厂商：通蔚生物
  • 产品价格：3580
  • 产品库存：35
  • 产品文档：
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简单介绍：
EID1抗原（重组蛋白）公司秉承“专注品质、信守承诺、积极沟通、chuang新服务”的企业文化积极参与生物领域的技术chuang新和技术服务，力求为我国科研事业添砖加瓦，严格的质控体系，建立和完善企业制度，创造性发展，客户的满意就是我们的宗旨。
详情介绍：
中文名称： EID1抗原（重组蛋白）

英文名称： EID1 Antigen (Recombinant Protein)

别     名：  CRI1; EID-1; RBP21; PTD014; C15orf3; PNAS-22; IRO45620

储     存：  冷冻（-20℃）

相关类别： 抗原

概     述：

Fusion protein corresponding to a region derived from 2-187 amino acids of human EID1

技术规格

Full name:

EP300 interacting inhibitor of differentiation 1

Synonyms:

CRI1; EID-1; RBP21; PTD014; C15orf3; PNAS-22; IRO45620

Swissprot:

Q9Y6B2

Gene Accession:

NP_055150

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

E1A-like inhibitor of differentiation-1 (EID-1), an acetyltransferase enzyme, binds both the retinoblastoma protein (Rb), a regulator of cell cycle and tissue specific transcription, and the adenovirus E1A-associated cellular p300 transcriptional co-activator protein. EID-1 inhibits cellular differentiation by blocking the histone acetyltransferase activity of p300. EID-1 also acetylates both histones and non-histone proteins such as NCOA3 co-activator. By acetylating histones, EID-1 gives a specific tag for transcriptional activation. In addition to binding Rb and p300, EID-1 also binds to phosphorylated CREB protein, mediating cAMP gene regulation. EID-1 augments the activity of phosphorylated CREB and activates transcription of cAMP responsive genes as a co-activator.





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