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  • 产品名称:EDN3抗原(重组蛋白)

  • 产品型号:1mg
  • 产品厂商:通蔚生物
  • 产品价格:3580
  • 产品库存:35
  • 产品文档:
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简单介绍:
EDN3抗原(重组蛋白)公司秉承“专注品质、信守承诺、积极沟通、chuang新服务”的企业文化积极参与生物领域的技术chuang新和技术服务,力求为我国科研事业添砖加瓦,严格的质控体系,建立和完善企业制度,创造性发展,客户的满意就是我们的宗旨。
详情介绍:
中文名称: EDN3抗原(重组蛋白)

英文名称: EDN3 Antigen (Recombinant Protein)

别     名:  ET3; ET-3; WS4B; HSCR4; PPET3

储     存:  冷冻(-20℃)

相关类别: 抗原

概     述:

Fusion protein corresponding to a region derived from 118-238 amino acids of human EDN3

技术规格

Full name:

endothelin 3

Synonyms:

ET3; ET-3; WS4B; HSCR4; PPET3

Swissprot:

P14138

Gene Accession:

BC008876

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

The protein encoded by this gene is a member of the endothelin family. Endothelins are endothelium-derived vasoactive peptides involved in a variety of biological functions. The active form of this protein is a 21 amino acid peptide processed from the precursor protein. The active peptide is a ligand for endothelin receptor type B (EDNRB). The interaction of this endothelin with EDNRB is essential for development of neural crest-derived cell lineages, such as melanocytes and enteric neurons. Mutations in this gene and EDNRB have been associated with Hirschsprung disease (HSCR) and Waardenburg syndrome (WS), which are congenital disorders involving neural crest-derived cells. Four alternatively spliced transcript variants encoding three distinct isoforms have been observed.





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