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  • 产品名称:DYNLL1抗原(重组蛋白)

  • 产品型号:1mg
  • 产品厂商:通蔚生物
  • 产品价格:3580
  • 产品库存:35
  • 产品文档:
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简单介绍:
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详情介绍:
中文名称: DYNLL1抗原(重组蛋白)

英文名称: DYNLL1 Antigen (Recombinant Protein)

别     名:  LC8; PIN; DLC1; DLC8; LC8a; DNCL1; hdlc1; DNCLC1

储     存:  冷冻(-20℃)

相关类别: 抗原

概     述:

Fusion protein corresponding to a region derived from 1-89 amino acids of human DYNLL1

技术规格

Full name:

dynein, light chain, LC8-type 1

Synonyms:

LC8; PIN; DLC1; DLC8; LC8a; DNCL1; hdlc1; DNCLC1

Swissprot:

P63167

Gene Accession:

NP_003737

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

Cytoplasmic dyneins are large enzyme complexes with a molecular mass of about 1,200 kD. They contain two force-producing heads formed primarily from dynein heavy chains, and stalks linking the heads to a basal domain, which contains a varying number of accessory intermediate chains. The complex is involved in intracellular transport and motility. The protein described in this record is a light chain and exists as part of this complex but also physically interacts with and inhibits the activity of neuronal nitric oxide synthase. Binding of this protein destabilizes the neuronal nitric oxide synthase dimer, a conformation necessary for activity, and it may regulate numerous biologic processes through its effects on nitric oxide synthase activity. Alternate transcriptional splice variants have been characterized.






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