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  • 产品名称：DRG1抗原（重组蛋白）

  • 产品型号：1mg
  • 产品厂商：通蔚生物
  • 产品价格：3580
  • 产品库存：35
  • 产品文档：
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简单介绍：
我司专业代理销售DRG1抗原（重组蛋白），质量保证，值得信赖，将以更上等的产品、更精湛的技术、更完善的服务、更饱满的热情服务于大家，如果你想了解更多关于抗体的详细信息，欢迎来电来函！
详情介绍：
中文名称： DRG1抗原（重组蛋白）

英文名称： DRG1 Antigen (Recombinant Protein)

别     名：  NEDD3

储     存：  冷冻（-20℃）

相关类别： 抗原

概     述：

Fusion protein corresponding to a region derived from C terminal 250 amino acids of human DRG1

技术规格

Full name:

developmentally regulated GTP binding protein 1

Synonyms:

NEDD3

Swissprot:

Q9Y295

Gene Accession:

BC019285

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

DRG1 (developmentally regulated GTP binding protein 1), also known as NEDD3 (neural precursor cell expressed developmentally down-regulated protein 3), is a 367 amino acid protein that localizes to the cytoplasm and belongs to the GTP1/OBG family. Expressed at high levels in heart, kidney and skeletal muscle and at lower levels in brain, liver, placenta, lung, colon and spleen, DRG1 binds to TAL1 and TAL2 and is thought to play a role in cell proliferation and differentiation, as well as in apoptosis, suggesting a role in tumor formation and metastasis. DRG1 is subject to polyubiquitination and sumoylation, the former of which induces proteolytic degradation. The gene encoding DRG1 maps to human chromosome 22, which houses over 500 genes and is the second smallest human chromosome. Mutations in several of the genes that map to chromosome 22 are involved in the development of Phelan-McDermid syndrome, Neurofibromatosis type 2, autism and schizophrenia.






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