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  • 产品名称：DOK4抗原（重组蛋白）

  • 产品型号：1mg
  • 产品厂商：通蔚生物
  • 产品价格：3580
  • 产品库存：35
  • 产品文档：
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简单介绍：
我司专业代理销售DOK4抗原（重组蛋白），质量保证，值得信赖，将以更上等的产品、更精湛的技术、更完善的服务、更饱满的热情服务于大家，如果你想了解更多关于抗体的详细信息，欢迎来电来函！
详情介绍：
中文名称： DOK4抗原（重组蛋白）

英文名称： DOK4 Antigen (Recombinant Protein)

储     存：  冷冻（-20℃）

相关类别： 抗原

概     述：

Fusion protein corresponding to a region derived from 7-237 amino acids of human DOK4

技术规格

Full name:

docking protein 4

Swissprot:

Q8TEW6

Gene Accession:

BC001540

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

Docking protein 4 is a protein that in humans is encoded by the DOK4 gene. Dok-4 is a 326 amino acid protein that contains one PH domain and one IRS-type PTB domain and belongs to the Dok family of interacting proteins. Expressed in a variety of tissues with highest expression in liver, heart, kidney and skeletal muscle, Dok-4 plays an important role in Ret-mediated neurite outgrowth and may link Ret with downstream effectors during neuronal differentiation. Additionally, Dok-4 is thought to play a positive role in the activation of MAPK pathways and may participate in T-cell induced immune system regulation. Overexpression of Dok-4 is associated with clear cell renal cell carcinoma, suggesting a role for Dok-4 in tumorigenesis.






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