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  • 产品名称：DNASE1抗原（重组蛋白）

  • 产品型号：1mg
  • 产品厂商：通蔚生物
  • 产品价格：3580
  • 产品库存：35
  • 产品文档：
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简单介绍：
我司专业代理销售DNASE1抗原（重组蛋白），质量保证，值得信赖，将以更上等的产品、更精湛的技术、更完善的服务、更饱满的热情服务于大家，如果你想了解更多关于抗体的详细信息，欢迎来电来函！
详情介绍：
中文名称： DNASE1抗原（重组蛋白）

英文名称： DNASE1 Antigen (Recombinant Protein)

别     名：  DNL1; DRNI

储     存：  冷冻（-20℃）

相关类别： 抗原

概     述：

Fusion protein corresponding to C terminal 260 amino acids of human DNASE1

技术规格

Full name:

deoxyribonuclease I

Synonyms:

DNL1; DRNI

Swissprot:

P24855

Gene Accession:

BC029437

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This gene encodes a member of the DNase family. This protein is stored in the zymogen granules of the nuclear envelope and functions by cleaving DNA in an endonucleolytic manner. At least six autosomal codominant alleles have been characterized, DNASE1*1 through DNASE1*6, and the sequence of DNASE1*2 represented in this record. Mutations in this gene have been associated with systemic lupus erythematosus (SLE), an autoimmune disease. A recombinant form of this protein is used to treat the one of the symptoms of cystic fibrosis by hydrolyzing the extracellular DNA in sputum and reducing its viscosity. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized.





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