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  • 产品名称:CYP17A1抗原(重组蛋白)

  • 产品型号:1mg
  • 产品厂商:通蔚生物
  • 产品价格:3580
  • 产品库存:35
  • 产品文档:
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详情介绍:
中文名称: CYP17A1抗原(重组蛋白)

英文名称: CYP17A1 Antigen (Recombinant Protein)
 
别     名:  CPT7; CYP17; S17AH; P450C17

储     存:  冷冻(-20℃)

相关类别: 抗原

概     述:

Fusion protein corresponding to a region derived from C terminal 250 amino acids of human CYP17A1

技术规格

Full name:

cytochrome P450, family 17, subfamily A, polypeptide 1

Synonyms:

CPT7; CYP17; S17AH; P450C17

Swissprot:

P05093

Gene Accession:

BC063388

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum. It has both 17alpha-hydroxylase and 17,20-lyase activities and is a key enzyme in the steroidogenic pathway that produces progestins, mineralocorticoids, glucocorticoids, androgens, and estrogens. Mutations in this gene are associated with isolated steroid-17 alpha-hydroxylase deficiency, 17-alpha-hydroxylase/17,20-lyase deficiency, pseudohermaphroditism, and adrenal hyperplasia.





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