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  • 产品名称：CPSF4抗原（重组蛋白）

  • 产品型号：1mg
  • 产品厂商：通蔚生物
  • 产品价格：3580
  • 产品库存：35
  • 产品文档：
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简单介绍：
我司专业代理销售CPSF4抗原（重组蛋白），质量保证，值得信赖，将以更上等的产品、更精湛的技术、更完善的服务、更饱满的热情服务于大家，如果你想了解更多关于抗体的详细信息，欢迎来电来函！
详情介绍：
中文名称： CPSF4抗原（重组蛋白）

英文名称： CPSF4 Antigen (Recombinant Protein)

别     名：  NAR; NEB1; CPSF30

储     存：  冷冻（-20℃）

相关类别： 抗原

概     述：

Fusion protein corresponding to a region derived from 1-244 amino acids of human CPSF4

技术规格

Full name:

cleavage and polyadenylation specific factor 4, 30kDa

Synonyms:

NAR; NEB1; CPSF30

Swissprot:

O95639

Gene Accession:

BC003101

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

Inhibition of the nuclear export of poly(A)-containing mRNAs caused by the influenza A virus NS1 protein requires its effector domain. The NS1 effector domain functionally interacts with the cellular 30 kDa subunit of cleavage and polyadenylation specific factor 4, an essential component of the 3' end processing machinery of cellular pre-mRNAs. In influenza virus-infected cells, the NS1 protein is physically associated with cleavage and polyadenylation specific factor 4, 30kD subunit. Binding of the NS1 protein to the 30 kDa protein in vitro prevents CPSF binding to the RNA substrate and inhibits 3' end cleavage and polyadenylation of host pre-mRNAs.





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