英文名称： CLIP1 Antigen (Recombinant Protein)
别 名： RSN; CLIP; CYLN1; CLIP170; CLIP-170
概 述：
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Full name: |
CAP-GLY domain containing linker protein 1 |
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Synonyms: |
RSN; CLIP; CYLN1; CLIP170; CLIP-170 |
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Swissprot: |
P30622 |
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Gene Accession: |
BC117209 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
The protein encoded by this gene links endocytic vesicles to microtubules. This gene is highly expressed in Reed-Sternberg cells of Hodgkin disease. Several transcript variants encoding different isoforms have been found for this gene. Binds to the plus end of microtubules and regulates the dynamics of the microtubule cytoskeleton. Promotes microtubule growth and microtubule bundling. Links cytoplasmic vesicles to microtubules and thereby plays an important role in intracellular vesicle trafficking. Plays a role macropinocytosis and endosome trafficking. |
