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  • 产品名称：BRCC3抗原（重组蛋白）

  • 产品型号：100 ug
  • 产品厂商：通蔚生物
  • 产品价格：800
  • 产品库存：35
  • 产品文档：
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简单介绍：
BRCC3抗原（重组蛋白）自成立以来，就注重企业信息化的建设，主要用于科研实验使用，采用了先进的内部供应链信息处理平台，保证客户订单的准确、高效处理，客户关系的管理系统和客户关系管理团队，能时间响应客户的售前、售后需求。
详情介绍：
中文名称： BRCC3抗原（重组蛋白）

英文名称： BRCC3 Antigen (Recombinant Protein)

别     名：  C6.1A; BRCC36; CXorf53

储     存：  冷冻（-20℃）

相关类别： 抗原

概     述：

Fusion protein corresponding to a region derived from 21-316 amino acids of human BRCC3

技术规格

Full name:

BRCA1/BRCA2-containing complex subunit 3

Synonyms:

C6.1A; BRCC36; CXorf53

Swissprot:

P46736

Gene Accession:

BC002999

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This gene encodes a subunit of the BRCA1-BRCA2-containing complex (BRCC), which is an E3 ubiquitin ligase. This complex plays a role in the DNA damage response, where it is responsible for the stable accumulation of BRCA1 at DNA break sites. The component encoded by this gene can specifically cleave Lys 63-linked polyubiquitin chains, and it regulates the abundance of these polyubiquitin chains in chromatin. The loss of this gene results in abnormal angiogenesis and is associated with syndromic moyamoya, a cerebrovascular angiopathy. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 5.





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