英文名称： BNIP3 Antigen (Recombinant Protein)
别 名： NIP3
概 述：
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Full name: |
BCL2/adenovirus E1B 19kDa interacting protein 3 |
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Synonyms: |
NIP3 |
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Swissprot: |
Q12983 |
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Gene Accession: |
BC021989 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
This gene is a member of the BCL2/adenovirus E1B 19 kd-interacting protein (BNIP) family. It interacts with the E1B 19 kDa protein, which protects cells from virally-induced cell death. The encoded protein also interacts with E1B 19 kDa-like sequences of BCL2, another apoptotic protector. This protein contains a BH3 domain and a transmembrane domain, which have been associated with pro-apoptotic function. The dimeric mitochondrial protein encoded by this gene is known to induce apoptosis, even in the presence of BCL2. |
