英文名称： BMX Antigen (Recombinant Protein)
别 名： ETK; PSCTK2; PSCTK3
储 存： 冷冻（-20℃）
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Full name: |
BMX non-receptor tyrosine kinase |
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Synonyms: |
ETK; PSCTK2; PSCTK3 |
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Swissprot: |
P51813 |
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Gene Accession: |
BC016652 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
This gene encodes a non-receptor tyrosine kinase belonging to the Tec kinase family. The protein contains a PH-like domain, which mediates membrane targeting by binding to phosphatidylinositol 3,4,5-triphosphate (PIP3), and a SH2 domain that binds to tyrosine-phosphorylated proteins and functions in signal transduction. The protein is implicated in several signal transduction pathways including the Stat pathway, and regulates differentiation and tumorigenicity of several types of cancer cells. Multiple alternatively spliced variants, encoding the same protein, have been identified. |
