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  • 产品名称:BAP1抗原(重组蛋白)

  • 产品型号:100 ug
  • 产品厂商:通蔚生物
  • 产品价格:800
  • 产品库存:35
  • 产品文档:
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简单介绍:
BAP1抗原(重组蛋白)自成立以来,就注重企业信息化的建设,主要用于科研实验使用,采用了先进的内部供应链信息处理平台,保证客户订单的准确、高效处理,客户关系的管理系统和客户关系管理团队,能时间响应客户的售前、售后需求。
详情介绍:
中文名称: BAP1抗原(重组蛋白)

英文名称: BAP1 Antigen (Recombinant Protein)

别     名:  UCHL2; hucep-6; HUCEP-13

储     存:  冷冻(-20℃)

相关类别: 抗原

概     述:

Fusion protein corresponding to a region derived from 366-596 amino acids of human BAP1

技术规格

Full name:

BRCA1 associated protein 1

Synonyms:

UCHL2; hucep-6; HUCEP-13

Swissprot:

Q92560

Gene Accession:

BC001596

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This gene belongs to the ubiquitin C-terminal hydrolase subfamily of deubiquitinating enzymes that are involved in the removal of ubiquitin from proteins. The encoded enzyme binds to the breast cancer type 1 susceptibility protein (BRCA1) via the RING finger domain of the latter and acts as a tumor suppressor. In addition, the enzyme may be involved in regulation of transcription, regulation of cell cycle and growth, response to DNA damage and chromatin dynamics. Germline mutations in this gene may be associated with tumor predisposition syndrome (TPDS), which involves increased risk of cancers including malignant mesothelioma, uveal melanoma and cutaneous melanoma.





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