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  • 产品名称:ARHGEF10抗原(重组蛋白)

  • 产品型号:1mg
  • 产品厂商:通蔚生物
  • 产品价格:3580
  • 产品库存:35
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详情介绍:


中文名称: ARHGEF10抗原(重组蛋白)

英文名称: ARHGEF10 Antigen (Recombinant Protein)

别     名:  GEF10

储     存:  冷冻(-20℃)

相关类别: 抗原

概     述:

Fusion protein corresponding to C terminal 300 amino acids of human ARHGEF10

技术规格

Full name:

Rho guanine nucleotide exchange factor (GEF) 10

Synonyms:

GEF10

Swissprot:

O15013

Gene Accession:

BC036809

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form complex with G proteins and stimulate Rho-dependent signals. ARHGEF10 (rho guanine nucleotide exchange factor 10), also known as GEF10 or KIAA0294, is a 1,369 amino acid protein that contains one DBL-homology domain and is thought to play a role in myelination of peripheral nerves, specifically during development. ARHGEF10 is expressed as four alternatively spliced isoforms that are present at low levels in ovary, lung, testis and kidney, with considerably higher expression in the central and peripheral nervous systems.






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