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  • 产品名称：ARHGEF3抗原（重组蛋白）

  • 产品型号：1mg
  • 产品厂商：通蔚生物
  • 产品价格：3580
  • 产品库存：35
  • 产品文档：
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简单介绍：
ARHGEF3抗原（重组蛋白）拥有上百名专业的技术人员，为您提供专业、耐心的服务，我们专业，所以值得信赖，信奉“客户至上”“诚信chuang新”；将竭尽所能，为您提供*便捷、*专业的采购服务，节省您的时间和成本。同时，完善的质量保证体系，提高企业的整体管理水平，一切努力和付出，惟愿助您一臂之力。
详情介绍：


中文名称： ARHGEF3抗原（重组蛋白）

英文名称： ARHGEF3 Antigen (Recombinant Protein)

别     名：  GEF3; STA3; XPLN

储     存：  冷冻（-20℃）

相关类别： 抗原

概     述：

Fusion protein corresponding to N terminal 202 amino acids of human ARHGEF3

技术规格

Full name:

Rho guanine nucleotide exchange factor (GEF) 3

Synonyms:

GEF3; STA3; XPLN

Swissprot:

Q9NR81

Gene Accession:

BC099715

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

Rho-like GTPases are involved in a variety of cellular processes, and they are activated by binding GTP and inactivated by conversion of GTP to GDP by their intrinsic GTPase activity. Guanine nucleotide exchange factors (GEFs) accelerate the GTPase activity of Rho GTPases by catalyzing their release of bound GDP. This gene encodes a guanine nucleotide exchange factor, which specifically activates two members of the Rho GTPase family: RHOA and RHOB, both of which have a role in bone cell biology. It has been identified that genetic variation in this gene plays a role in the determination of bone mineral density (BMD), indicating the implication of this gene in postmenopausal osteoporosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.






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