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  • 产品名称:AANAT抗原(重组蛋白)

  • 产品型号:1mg
  • 产品厂商:通蔚生物
  • 产品价格:3580
  • 产品库存:35
  • 产品文档:
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简单介绍:
AANAT抗原(重组蛋白)公司是一家专业从事生物科研项目的企业,经销优异化生物试剂,国内外知名品牌ELISA试剂盒,标准品|对照品,抗体,培养基,血清的科研生物产品,竭诚为您提供行内*全、*新的产品信息。欢迎来电咨询!
详情介绍:
中文名称: AANAT抗原(重组蛋白)

英文名称: AANAT Antigen (Recombinant Protein)

别     名:  DSPS; SNAT

储     存:  冷冻(-20℃)

相关类别: 抗原

概     述:

Fusion protein corresponding to a region derived from 35-194 amino acids of human AANAT

技术规格:

Full name:

aralkylamine N-acetyltransferase

Synonyms:

DSPS; SNAT

Swissprot:

Q16613

Gene Accession:

BC069434

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

The protein encoded by this gene belongs to the acetyltransferase superfamily. It is the penultimate enzyme in melatonin synthesis and controls the night/day rhythm in melatonin production in the vertebrate pineal gland. Melatonin is essential for the function of the circadian clock that influences activity and sleep. This enzyme is regulated by cAMP-dependent phosphorylation that promotes its interaction with 14-3-3 proteins and thus protects the enzyme against proteasomal degradation. This gene may contribute to numerous genetic diseases such as delayed sleep phase syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.





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