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  • 产品名称：ZNF354A 抗原（重组蛋白）

  • 产品型号：1mg
  • 产品厂商：通蔚生物
  • 产品价格：3580
  • 产品库存：35
  • 产品文档：
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简单介绍：
ZNF354A 抗原（重组蛋白）关抗体在生物行业的发展国家给予了极大的重视，更多地侧重于科研的投入，服务和业务在同行获得一致好评，其立足于生命科学领域，全力打造高品质生物科技产品链和技术服务链，也具备丰富的管理经验。
详情介绍：


中文名称： ZNF354A 抗原（重组蛋白）

英文名称： ZNF354A Antigen (Recombinant Protein)

别     名：  zinc finger protein 354A; EZNF; HKL1; KID1; KID-1; TCF17; HEL104

相关类别： 抗原

储     存：  冷冻（-20℃）

概     述

Fusion protein corresponding to a region derived from 406-605 amino acids of human ZNF354A

技术规格

Full name:

zinc finger protein 354A

Synonyms:

EZNF; HKL1; KID1; KID-1; TCF17; HEL104

Swissprot:

O60765

Gene Accession:

BC047105

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

ZNF354A, also called EZNF, KID-1 or TCF17, belongs to the Krüppel C2H2-type zinc-finger family of proteins that contain KRAB domains and act as transcriptional regulators. Expressed primarily in the ***** kidney, ZNF354A is a transcriptional repressor that plays a role in late renal development and is suppressed after renal ischemia. The N-terminus of ZNF354A contains the KRAB domain which confers transcriptional repressor activity, while the C-terminus contains multiple Cys2His2-zinc fingers. ZNF354A is located in the nucleolus and is thought to specifically influence development of the proximal tubule by shutting off dispensable or inhibitory genes. Reduced ZNF354A expression prevents proper cell differentiation and may, therefore, be implicated in renal carcinoma.






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