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  • 产品名称:ZNF217 抗原(重组蛋白)

  • 产品型号:100ug
  • 产品厂商:通蔚生物
  • 产品价格:800
  • 产品库存:35
  • 产品文档:
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简单介绍:
ZNF217 抗原(重组蛋白)关抗体在生物行业的发展国家给予了极大的重视,更多地侧重于科研的投入,服务和业务在同行获得一致好评,其立足于生命科学领域,全力打造高品质生物科技产品链和技术服务链,也具备丰富的管理经验。
详情介绍:

中文名称: ZNF217 抗原(重组蛋白)


英文名称: ZNF217 Antigen (Recombinant Protein)

别     名:  zinc finger protein 217; ZABC1

储     存:  冷冻(-20℃)

相关类别: 抗原
 
概     述

Fusion protein corresponding to N terminal 200 amino acids of human ZNF217

技术规格

Full name:

zinc finger protein 217

Synonyms:

ZABC1

Swissprot:

O75362

Gene Accession:

BC113427

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

ZNF217, also known as ZABC1, is a zinc finger protein belonging to the Krüppel C2H2-type zinc-finger protein family. It localizes to the nucleus and may play a role in transcriptional repression of a variety of genes through the recruitment of co-repressor complexes containing proteins such as CtBP, HDAC1 and HDAC2. In addition, ZNF217 participates in cell differentiation and appears to function as an oncogene. Expression of ZNF217 is amplified in various tumors and overexpression of the protein can attenuate apoptotic signals and lead to epithelial cell immortalization.Binds to the promoters of target genes and functions as repressor. Promotes cell proliferation and antagonizes cell death. Promotes phosphorylation of AKT1 at 'Ser-473'.







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