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  • 产品名称:ZNF131 抗原(重组蛋白)

  • 产品型号:1mg
  • 产品厂商:通蔚生物
  • 产品价格:3580
  • 产品库存:35
  • 产品文档:
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简单介绍:
ZNF131 抗原(重组蛋白)奉行以人为本、唯才善用,提倡人是核心资本,公平合理并创造性地使用人才,尽可能的给员工提供足够的舞台去发挥去成长,公司尊重人,尊重每一位员工的个性,依托这样的人才观,将进一步完善科学合理的人力资源管理机制,造就一个良好的人才成长空间。
详情介绍:
中文名称: ZNF131 抗原(重组蛋白)

英文名称: ZNF131 Antigen (Recombinant Protein)

别     名:  zinc finger protein 131; ZBTB35; pHZ-10

相关类别: 抗原

储     存:  冷冻(-20℃) 

概     述

Fusion protein corresponding to a region derived from 424-623 amino acids of human ZNF131

技术规格

Full name:

zinc finger protein 131

Synonyms:

ZBTB35; pHZ-10

Swissprot:

P52739

Gene Accession:

BC035875

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Krüppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. As a member of the krueppel C2H2-type zinc-finger protein family, ZNF131 (Zinc finger protein 131) is a 623 amino acid nuclear protein that contains one BTB (POZ) domain and six C2H2-type zinc fingers. With predominant expression found in brain, it is likely that ZNF131 plays a role as a transcription regulator during development and organogenesis of the ***** central nervous system. ZNF131 also represses ER? (Estrogen receptor alpha)-mediated transactivation by interrupting ER? binding to the estrogen-response element. There are two isoforms of ZNF131 that are produced as a result of alternative splicing events.






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