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  • 产品名称：VRK1 抗原（重组蛋白）

  • 产品型号：1mg
  • 产品厂商：通蔚生物
  • 产品价格：3580
  • 产品库存：35
  • 产品文档：
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简单介绍：
VRK1 抗原（重组蛋白）奉行以人为本、唯才善用，提倡人是核心资本，公平合理并创造性地使用人才，尽可能的给员工提供足够的舞台去发挥去成长，公司尊重人，尊重每一位员工的个性，依托这样的人才观，将进一步完善科学合理的人力资源管理机制，造就一个良好的人才成长空间。
详情介绍：
中文名称： VRK1 抗原（重组蛋白）

英文名称： VRK1 Antigen (Recombinant Protein)

别     名：  vaccinia related kinase 1; PCH1; PCH1A

相关类别： 抗原

储     存：  冷冻（-20℃）

概     述

Fusion protein corresponding to a region derived from 197-396 amino acids of human VRK1

技术规格

Full name:

vaccinia related kinase 1

Synonyms:

PCH1; PCH1A

Swissprot:

Q99986

Gene Accession:

BC113510

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This gene encodes a member of the vaccinia-related kinase (VRK) family of serine/threonine protein kinases. This gene is widely expressed in human tissues and has increased expression in actively dividing cells, such as those in testis, thymus, fetal liver, and carcinomas. Its protein localizes to the nucleus and has been shown to promote the stability and nuclear accumulation of a transcriptionally active p53 molecule and, in vitro, to phosphorylate Thr18 of p53 and reduce p53 ubiquitination. This gene, therefore, may regulate cell proliferation. This protein also phosphorylates histone, casein, and the transcription factors ATF2 (activating transcription factor 2) and c-JUN.





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