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  • 产品名称：TMEM256 抗原（重组蛋白）

  • 产品型号：1mg
  • 产品厂商：通蔚生物
  • 产品价格：3580
  • 产品库存：35
  • 产品文档：
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简单介绍：
TMEM256 抗原（重组蛋白）以强大的专业背景、上等的客户服务、完备的产品供应和深厚的人脉资源，在同行业中保持良好的企业形象和竞争优势，在市场竞争日益激烈的今天，将始终坚持信誉立业、以人为本、质量**、诚信服务的宗旨，不断拼搏，开拓进取，与各界朋友携手共创美好未来。
详情介绍：

中文名称： TMEM256 抗原（重组蛋白）

英文名称： TMEM256 Antigen (Recombinant Protein)

别     名：  transmembrane protein 256; C17orf61

储     存：  冷冻（-20℃）     

相关类别： 抗原

概     述

Fusion protein corresponding to a region derived from 30-113 amino acids of human TMEM256

技术规格

Full name:

transmembrane protein 256

Synonyms:

C17orf61

Swissprot:

Q8N2U0

Gene Accession:

BC030270

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

TMEM256, also known as C17orf61, C17orf61 (chromosome 17 open reading frame 61) is a 113 amino acid protein that is encoded by a gene mapping to human chromosome 17. Chromosome 17 makes up over 2.5% of the human genome with about 81 million bases encoding over 1,200 genes. Two key tumor suppressor genes are associated with chromosome 17, namely, p53 and BRCA1. Tumor suppressor p53 is necessary for maintenance of cellular genetic integrity by moderating cell fate through DNA repair versus cell death. Malfunction or loss of p53 expression is associated with malignant cell growth and Li-Fraumeni syndrome. Like p53, BRCA1 is directly involved in DNA repair, specifically it is recognized as a genetic determinant of early onset breast cancer and predisposition to cancers of the ovary, colon, prostate gland and fallopian tubes. Chromosome 17 is also linked to neurofibromatosis, a condition characterized by neural and epidermal lesions, and dysregulated Schwann cell growth. Alexander disease, Birt-Hogg-Dube syndrome and Canavan disease are also associated with chromosome 17.





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