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  • 产品名称：TEAD2 抗原（重组蛋白）

  • 产品型号：100ug
  • 产品厂商：通蔚生物
  • 产品价格：800
  • 产品库存：35
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简单介绍：
TEAD2 抗原（重组蛋白）以诚信为本，努力打造上等的品牌，为您提供全方位的售中、售后服务，具有上等的技术团队和上等的产品引入国内市场，满足国内广大客户的需求。
详情介绍：



中文名称： TEAD2 抗原（重组蛋白）

英文名称： TEAD2 Antigen (Recombinant Protein)

别     名：  TEA domain transcription factor 2; ETF; TEF4; TEF-4; TEAD-2

储     存：  冷冻（-20℃）

相关类别： 抗原

概     述

Fusion protein corresponding to a region derived from 248-447 amino acids of human TEAD2

技术规格

Full name:

TEA domain transcription factor 2

Synonyms:

ETF; TEF4; TEF-4; TEAD-2

Swissprot:

Q15562

Gene Accession:

BC007556

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein MST1/MST2, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Acts by mediating gene expression of YAP1 and WWTR1/TAZ, thereby regulating cell proliferation, migration and epithelial mesenchymal transition (EMT) induction. Binds to the SPH and GT-IIC 'enhansons' (5'-GTGGAATGT-3'). May be involved in the gene regulation of neural development. Binds to the M-CAT motif.







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