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  • 产品名称：TCIM 抗原（重组蛋白）

  • 产品型号：100ug
  • 产品厂商：通蔚生物
  • 产品价格：800
  • 产品库存：35
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详情介绍：



中文名称： TCIM 抗原（重组蛋白）

英文名称： TCIM Antigen (Recombinant Protein)

别     名：  transcriptional and immune response regulator; TC1; TC-1; C8orf4

储     存：  冷冻（-20℃）

相关类别： 抗原

概     述

Fusion protein corresponding to a region derived from 1-106 amino acids of human TCIM

技术规格

Full name:

transcriptional and immune response regulator

Synonyms:

TC1; TC-1; C8orf4

Swissprot:

Q9NR00

Gene Accession:

BC020623

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This gene encodes a small, monomeric, predominantly unstructured protein that functions as a positive regulator of the Wnt/beta-catenin signaling pathway. This protein interacts with a repressor of beta-catenin mediated transcription at nuclear speckles. It is thought to competitively block interactions of the repressor with beta-catenin, resulting in up-regulation of beta-catenin target genes. The encoded protein may also play a role in the NF-kappaB and ERK1/2 signaling pathways. Expression of this gene may play a role in the proliferation of several types of cancer including thyroid cancer, breast cancer and hematological malignancies. [provided by RefSeq, Nov 2011]







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