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  • 产品名称：TAB1 抗原（重组蛋白）

  • 产品型号：100ug
  • 产品厂商：通蔚生物
  • 产品价格：800
  • 产品库存：35
  • 产品文档：
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详情介绍：



中文名称： TAB1 抗原（重组蛋白）

英文名称： TAB1 Antigen (Recombinant Protein)

别     名：  TGF-beta activated kinase 1/MAP3K7 binding protein 1; 3'-Tab1; MAP3K7IP1

储     存：  冷冻（-20℃）

相关类别： 抗原

概     述

Fusion protein corresponding to a region derived from 64-368 amino acids of human TAB1

技术规格

Full name:

TGF-beta activated kinase 1/MAP3K7 binding protein 1

Synonyms:

3'-Tab1; MAP3K7IP1

Swissprot:

Q15750

Gene Accession:

BC050554

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

The protein encoded by this gene was identified as a regulator of the MAP kinase kinase kinase MAP3K7/TAK1, which is known to mediate various intracellular signaling pathways, such as those induced by TGF beta, interleukin 1, and WNT-1. This protein interacts and thus activates TAK1 kinase. It has been shown that the C-terminal portion of this protein is sufficient for binding and activation of TAK1, while a portion of the N-terminus acts as a dominant-negative inhibitor of TGF beta, suggesting that this protein may function as a mediator between TGF beta receptors and TAK1.









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