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  • 产品名称：SHC1 抗原（重组蛋白）

  • 产品型号：100ug
  • 产品厂商：通蔚生物
  • 产品价格：800
  • 产品库存：35
  • 产品文档：
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简单介绍：
SHC1 抗原（重组蛋白）科研探索耗脑力，精品试剂添助力，千挑万选消财力，产品种类多，价格实惠，质量有保证，准确的交货时间，并且提供免费检测服务！我司为客户提供精质产品和上等服务的理念，特为广大客户送出科研好礼。
详情介绍：


中文名称： SHC1 抗原（重组蛋白）

英文名称： SHC1 Antigen (Recombinant Protein)

别     名：  SHC adaptor protein 1; SHC; SHCA

储     存：  冷冻（-20℃）

相关类别： 抗原

概     述

Fusion protein corresponding to a region derived from 384-583 amino acids of human SHC1

技术规格

Full name:

SHC adaptor protein 1

Synonyms:

SHC; SHCA

Swissprot:

P29353

Gene Accession:

BC014158

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This gene encodes three main isoforms that differ in activities and subcellular location. While all three are adapter proteins in signal transduction pathways, the longest (p66Shc) may be involved in regulating life span and the effects of reactive oxygen species. The other two isoforms, p52Shc and p46Shc, link activated receptor tyrosine kinases to the Ras pathway by recruitment of the GRB2/SOS complex. p66Shc is not involved in Ras activation. Unlike the other two isoforms, p46Shc is targeted to the mitochondrial matrix. Several transcript variants encoding different isoforms have been found for this gene.








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