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  • 产品名称:SELENOP 抗原(重组蛋白)

  • 产品型号:100ug
  • 产品厂商:通蔚生物
  • 产品价格:800
  • 产品库存:35
  • 产品文档:
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简单介绍:
SELENOP 抗原(重组蛋白)一路走来依靠丰富的经验、优良的抗体品质、充足的库存、准确的交货时间、具竞争力的价格优势等成为试剂盒行业的遥遥优越者,当然这些都离不开大家的支持,让客户满意,才是我们永恒的追求!
详情介绍:

中文名称: SELENOP 抗原(重组蛋白) 

英文名称: SELENOP Antigen (Recombinant Protein)

相关类别: 抗原

储     存:  冷冻(-20℃) 避光  

概     述

Fusion protein corresponding to a region derived from 62-211 amino acids of human SELENOP

技术规格


Full name:

selenoprotein P

Synonyms:

SeP; SELP; SEPP; SEPP1

Swissprot:

P49908

Gene Accession:

BC058919

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This gene encodes a selenoprotein that is predominantly expressed in the liver and secreted into the plasma. This selenoprotein is unique in that it contains multiple selenocysteine (Sec) residues per polypeptide (10 in human), and accounts for most of the selenium in plasma. It has been implicated as an extracellular antioxidant, and in the transport of selenium to extra-hepatic tissues via apolipoprotein E receptor-2 (apoER2). Mice lacking this gene exhibit neurological dysfunction, suggesting its importance in normal brain function. Sec is encoded by the UGA codon, which normally signals translation termination. The 3' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, designated the Sec insertion sequence (SECIS) element, that is necessary for the recognition of UGA as a Sec codon, rather than as a stop signal. The mRNA for this selenoprotein contains two SECIS elements. The use of alternative polyadenylation sites, one located in between the two SECIS elements, results in two populations of mRNAs containing either both (predominant) or just the upstream SECIS element (PMID:27881738). Alternatively spliced transcript variants have also been found for this gene.





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