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  • 产品名称:RNF128 抗原(重组蛋白)

  • 产品型号:100ug
  • 产品厂商:通蔚生物
  • 产品价格:800
  • 产品库存:35
  • 产品文档:
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简单介绍:
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详情介绍:
中文名称: RNF128 抗原(重组蛋白)

英文名称: RNF128 Antigen (Recombinant Protein)

别     名:  ring finger protein 128; GRAIL

储     存:  冷冻(-20℃)

相关类别: 抗原

概     述

Fusion protein corresponding to a region derived from 39-207 amino acids of human RNF128

技术规格

Full name:

ring finger protein 128

Synonyms:

GRAIL

Swissprot:

Q8TEB7

Gene Accession:

BC063404

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

The protein encoded by this gene is a type I transmembrane protein that localizes to the endocytic pathway. This protein contains a RING zinc-finger motif and has been shown to possess E3 ubiquitin ligase activity. Expression of this gene in retrovirally transduced T cell hybridoma significantly inhibits activation-induced IL2 and IL4 cytokine production. Induced expression of this gene was observed in anergic CD4(+) T cells, which suggested a role in the induction of anergic phenotype. Alternatively spliced transcript variants encoding distinct isoforms have been reported.







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