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  • 产品名称:RGS14 抗原(重组蛋白)

  • 产品型号:100ug
  • 产品厂商:通蔚生物
  • 产品价格:800
  • 产品库存:35
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详情介绍:
中文名称: RGS14 抗原(重组蛋白)

英文名称: RGS14 Antigen (Recombinant Protein)

别     名:  regulator of G protein signaling 14

储     存:  冷冻(-20℃)

相关类别: 抗原

概     述

Fusion protein corresponding to a region derived from 302-566 amino acids of human RGS14

技术规格

Full name:

regulator of G protein signaling 14

Swissprot:

O43566

Gene Accession:

BC014094

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This gene encodes a member of the regulator of G-protein signaling family. This protein contains one RGS domain, two Raf-like Ras-binding domains (RBDs), and one GoLoco domain. The protein attenuates the signaling activity of G-proteins by binding, through its GoLoco domain, to specific types of activated, GTP-bound G alpha subunits. Acting as a GTPase activating protein (GAP), the protein increases the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized.







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