英文名称: RGS1 Antigen (Recombinant Protein)
别 名: regulator of G-protein signaling 1; 1R20; BL34; IER1; IR20; HEL-S-87
储 存: 冷冻(-20℃)
相关类别: 抗原
概 述
| Full name: | regulator of G-protein signaling 1 | 
| Synonyms: | 1R20; BL34; IER1; IR20; HEL-S-87 | 
| Swissprot: | Q08116 | 
| Gene Accession: | BC015510 | 
| Purity: | >85%, as determined by Coomassie blue stained SDS-PAGE | 
| Expression system: | Escherichia coli | 
| Tags: | His tag C-Terminus, GST tag N-Terminus | 
| Background: | This gene encodes a member of the regulator of G-protein signalling family. This protein is located on the cytosolic side of the plasma membrane and contains a conserved, 120 amino acid motif called the RGS domain. The protein attenuates the signalling activity of G-proteins by binding to activated, GTP-bound G alpha subunits and acting as a GTPase activating protein (GAP), increasing the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal. | 

