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  • 产品名称：CDKN2A 抗原

  • 产品型号：1mg
  • 产品厂商：通蔚生物
  • 产品价格：350
  • 产品库存：35
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简单介绍：
CDKN2A 抗原（重组蛋白）深获顾客信赖外，更带给顾客喜悦和满足，公司员工亦因此找到工作及生活的意义，将紧跟经营管理和科学技术发展的步伐，提升和加强公司的市场竞争力，同心协力，尽展创意，致力于可持续发展、向社会尽责的企业宗旨。
详情介绍：
中文名称： CDKN2A 抗原 

英文名称： CDKN2A Antigen

相关类别： 抗原

储     存：  冷冻（-20℃） 

概     述

Synthetic peptide corresponding to a region derived from 144-156 amino acids of human cyclin-dependent kinase inhibitor 2A

技术规格

Background

This gene generates several transcript variants which differ in their first exons. At least three alternatively spliced variants encoding distinct proteins have been reported, two of which encode structurally related isoforms known to function as inhibitors of CDK4 kinase. The remaining transcript includes an alternate first exon located 20 Kb upstream of the remainder of the gene; this transcript contains an alternate open reading frame (ARF) that specifies a protein which is structurally unrelated to the products of the other variants. This ARF product functions as a stabilizer of the tumor suppressor protein p53 as it can interact with, and sequester, the E3 ubiquitin-protein ligase MDM2, a protein responsible for the degradation of p53.

Gene Accession

NP_000068

Swissprot

P42771

Synonyms

ARF; MLM; P14; P16; P19; CMM2; INK4; MTS1; TP16; CDK4I; CDKN2; INK4A; MTS-1; P14ARF; P19ARF; P16INK4; P16INK4A; P16-INK4A

Full name

cyclin-dependent kinase inhibitor 2A







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