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  • 产品名称：CCDC181 抗原（重组蛋白）

  • 产品型号：1mg
  • 产品厂商：通蔚生物
  • 产品价格：3580
  • 产品库存：35
  • 产品文档：
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简单介绍：
CCDC181 抗原（重组蛋白）公司的服务和业务网络遍及国内，在同行获得一致好评，将一直伴随着顾客的信赖成长，规模和抗体种类日益扩大和更新，一直秉承着代理上等品牌的产品，服务好每一位顾客，将好的科学技术和方法推荐给顾客的服务宗旨。
详情介绍：

中文名称： CCDC181 抗原（重组蛋白）

英文名称： CCDC181 Antigen (Recombinant Protein)

别     名：  coiled-coil domain containing 181; C1orf114

储     存：  冷冻（-20℃） 

相关类别： 抗原

概     述

Fusion protein corresponding to a region derived from 173-372 amino acids of human CCDC181

技术规格

Full name:

coiled-coil domain containing 181

Synonyms:

C1orf114

Swissprot:

Q5TID7

Gene Accession:

BC026073

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

CCDC181, also known as C1orf114, chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1. A breakpoint has been identified in 1q which disrupts the DISC1 gene and is linked to schizophrenia. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma. The C1orf114 gene product has been provisionally designated C1orf114 pending further characterization.




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